A placebo-controlled study of trazodone in bulimia nervosa

J Clin Psychopharmacol. 1989 Aug;9(4):254-9.

Abstract

Forty-two women who met the new narrower criteria for bulimia nervosa of DSM-III-R completed a placebo-controlled double-blind study with trazodone. The drug proved significantly superior to placebo, both in measures of frequency of binge eating and vomiting and in the patients' subjective assessments of improvement. Trazodone produced few adverse effects.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Bulimia / drug therapy*
  • Bulimia / psychology
  • Clinical Trials as Topic
  • Depressive Disorder / drug therapy
  • Depressive Disorder / psychology
  • Dose-Response Relationship, Drug
  • Double-Blind Method
  • Feeding Behavior / drug effects
  • Female
  • Humans
  • Random Allocation
  • Trazodone / adverse effects
  • Trazodone / therapeutic use*

Substances

  • Trazodone