Raynaud's phenomenon and disease

Med Clin North Am. 1989 Sep;73(5):1127-41. doi: 10.1016/s0025-7125(16)30623-x.


Maurice Raynaud initiated the discussion of cold-induced vasospasm over 125 years ago. Research has shown that the physiology of Raynaud's involves a complex interaction in both local and systemic factors. Although a multitude of laboratory tests are available to help evaluate the prognosis of Raynaud's phenomenon, patient history remains the most reliable method of diagnosis. There are a variety of treatment modalities available. The treatment program should be tailored to the severity and etiology of the disease.

Publication types

  • Review

MeSH terms

  • Humans
  • Raynaud Disease* / diagnosis
  • Raynaud Disease* / etiology
  • Raynaud Disease* / therapy