Detection of a PDGFRB fusion in refractory CMML without eosinophilia: A case for broad spectrum tumor profiling

Leuk Res Rep. 2015 Sep 24;4(2):70-1. doi: 10.1016/j.lrr.2015.07.002. eCollection 2015.


In this case report, we describe a refractory CMML case without eosinophilia harboring a PDGFRB rearrangement leading to a favorable response with imatinib. We believe this case demonstrates the utility of broad spectrum genomic profiling in refractory CMML cases as an opportunity to uncover additional treatment options.

Publication types

  • Case Reports