We are all aware of growing environmental concerns, and the need to provide new and improved means for maintaining a healthy environment. Pesticides are the only toxic chemicals released intentionally into the environment to kill living organisms. Pesticide detection and destruction has become a very important and inevitable area of research because of the rapid expansion of agriculture and stringent environmental protection acts. Electrochemistry offers promising approaches for the determination and destruction of pollutants. The interaction of nanotechnology opens the possibility for a wide variety of chemical and biological research topics and day-to-day applications at the molecular and cellular level. Nanotechnology has allowed introducing novel strategies in sensors and biosensor research. Recently researchers have become increasingly interested in nanomaterial assisted electrochemical techniques. This review emphasizes the recent developments of electrochemical methods combined with nanotechnology for sensing and decontamination of pesticides.