Corticosteroids in rheumatoid arthritis

Semin Arthritis Rheum. 1989 Aug;19(1):9-21. doi: 10.1016/0049-0172(89)90083-8.


This report has presented evidence to support a disease-modifying role for corticosteroids in rheumatoid arthritis. It would appear that the efficacy of these agents in retarding the destructive course of rheumatoid disease has been substantially underestimated. Consideration for more liberal use of corticosteroids in the management of rheumatoid arthritis is warranted. Further study on new approaches to corticosteroid delivery is proposed.

Publication types

  • Clinical Trial
  • Historical Article
  • Review

MeSH terms

  • Adrenal Cortex Hormones / adverse effects
  • Adrenal Cortex Hormones / history
  • Adrenal Cortex Hormones / therapeutic use*
  • Arthritis, Rheumatoid / drug therapy*
  • Biomechanical Phenomena
  • Clinical Trials as Topic
  • Drug Administration Schedule
  • Drug Carriers
  • History, 20th Century
  • Humans
  • Injections, Intra-Articular
  • Liposomes
  • Pulsatile Flow
  • United States


  • Adrenal Cortex Hormones
  • Drug Carriers
  • Liposomes