[Positive urine pneumococcal antigen test and vaccination]

Med Clin (Barc). 2016 Apr 15;146(8):346-7. doi: 10.1016/j.medcli.2015.10.019. Epub 2015 Dec 24.
[Article in Spanish]

Abstract

Introduction and objective: Although urine pneumococcal antigen is an useful test, it has false positives such as pneumococcal vaccination.

Material and methods: Positive urine pneumococcal antigen in Hospital de Denia (January-February/2015). We studied epidemiological, radiological and microbiological variables as well as previous pneumococcal vaccination (neumo-23 and/or neumo-13).

Results: Urine pneumococcal antigen test was positive in 12.4% of 385 cases. Only 33.3% of positive cases had pneumonia in chest X-ray, and 35.4% of patients had previous pneumococcal vaccination. In most cases (87.5%), an antibiotic was prescribed.

Conclusions: Pneumococcal vaccination can produce a false positive result in the urine pneumococcal antigen test in clinical practice, leading to an unnecessary prescription of antibiotics.

Keywords: False positive; Falso positivo; Neumococo; Pneumococcus; Vaccination; Vacunación.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Antigens, Bacterial / urine*
  • Biomarkers / urine
  • Child
  • Child, Preschool
  • False Positive Reactions
  • Female
  • Humans
  • Infant
  • Male
  • Middle Aged
  • Pneumococcal Vaccines / immunology*
  • Pneumonia, Pneumococcal / diagnosis*
  • Pneumonia, Pneumococcal / microbiology
  • Pneumonia, Pneumococcal / urine
  • Streptococcus pneumoniae / immunology*
  • Young Adult

Substances

  • Antigens, Bacterial
  • Biomarkers
  • Pneumococcal Vaccines