Allergic Reactions to Pine Nut: A Review

J Investig Allergol Clin Immunol. 2015;25(5):329-33.

Abstract

Pine nut is a nutrient-rich food with a beneficial impact on human health. The many bioactive constituents of pine nut interact synergistically to affect human physiology in a favorable way. However, pine nut can trigger dangerous allergic reactions. Severe anaphylactic reactions to pine nut accounted for most of the 45 cases reported in the scientific literature. Pine nut allergy seems to be characterized by low IgE cross-reactivity with other commonly consumed nuts and a high monosensitization rate. The present review provides updated information on allergic reactions to pine nut, molecular characterization of its allergens, and potential homologies with other nut allergens.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • 2S Albumins, Plant / immunology
  • Allergens / immunology*
  • Cross Reactions / immunology
  • Humans
  • Immunoglobulin E / immunology*
  • Nut Hypersensitivity / immunology*
  • Nuts / immunology*
  • Pinus / immunology*
  • Plant Proteins / immunology
  • Profilins / immunology
  • Seed Storage Proteins / immunology

Substances

  • 2S Albumins, Plant
  • Allergens
  • Plant Proteins
  • Profilins
  • Seed Storage Proteins
  • legumin protein, plant
  • Immunoglobulin E
  • vicilin protein, plant