Incomplete Estrogen Suppression With Gonadotropin-Releasing Hormone Agonists May Reduce Clinical Efficacy in Premenopausal Women With Early Breast Cancer

J Clin Oncol. 2016 May 10;34(14):1580-3. doi: 10.1200/JCO.2015.62.3728. Epub 2016 Jan 4.

Authors

Mitch Dowsett¹, Per E Lønning², Nancy E Davidson³

Affiliations

¹ Royal Marsden Hospital, London, United Kingdom mitch.dowsett@icr.ac.uk.
² University of Bergen and Haukeland University Hospital, Bergen, Norway.
³ University of Pittsburgh Cancer Institute and UPMC CancerCenter, Pittsburgh, PA.

PMID: 26729430
DOI: 10.1200/JCO.2015.62.3728

No abstract available

MeSH terms

Adult
Antineoplastic Agents, Hormonal / therapeutic use*
Breast Neoplasms / drug therapy*
Estrogens / chemistry*
Female
Gonadotropin-Releasing Hormone / agonists*
Humans
Middle Aged
Premenopause / drug effects*
Treatment Outcome

Substances

Antineoplastic Agents, Hormonal
Estrogens
Gonadotropin-Releasing Hormone