Abrupt Relapse of ALK-Positive Lymphoma after Discontinuation of Crizotinib

N Engl J Med. 2016 Jan 7;374(1):95-6. doi: 10.1056/NEJMc1511045.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Anaplastic Lymphoma Kinase
  • Child, Preschool
  • Crizotinib
  • Female
  • Humans
  • Lymphoma, Large-Cell, Anaplastic / drug therapy*
  • Polymerase Chain Reaction
  • Protein Kinase Inhibitors / therapeutic use*
  • Pyrazoles / therapeutic use*
  • Pyridines / therapeutic use*
  • RNA, Messenger / blood
  • Receptor Protein-Tyrosine Kinases / blood
  • Receptor Protein-Tyrosine Kinases / genetics
  • Recurrence

Substances

  • Protein Kinase Inhibitors
  • Pyrazoles
  • Pyridines
  • RNA, Messenger
  • Crizotinib
  • ALK protein, human
  • Anaplastic Lymphoma Kinase
  • Receptor Protein-Tyrosine Kinases