In-vitro assessment of Jurkat T-cells response to 1966 MHz electromagnetic fields in a GTEM cell

Nektarios Moraitis; Maria Christopoulou; Konstantina S Nikita; Georgia-Persephoni Voulgaridou; Ioannis Anestopoulos; Mihalis I Panagiotidis; Aglaia Pappa

doi:10.1109/EMBC.2015.7318922

In-vitro assessment of Jurkat T-cells response to 1966 MHz electromagnetic fields in a GTEM cell

Annu Int Conf IEEE Eng Med Biol Soc. 2015:2015:2592-5. doi: 10.1109/EMBC.2015.7318922.

Authors

Nektarios Moraitis, Maria Christopoulou, Konstantina S Nikita, Georgia-Persephoni Voulgaridou, Ioannis Anestopoulos, Mihalis I Panagiotidis, Aglaia Pappa

PMID: 26736822
DOI: 10.1109/EMBC.2015.7318922

Abstract

This paper presents the experimental configuration and procedure as well as the in-vitro assessment of Jurkat T-cells response to 1966 MHz exposure of modulated and unmodulated electromagnetic signals within a Gigahertz Transverse Electro-Magnetic (GTEM) cell. Different combinations of electric field intensity, exposure duration and modulation schemes were applied. Exposures at continuous wave (CW) signal at low intensity levels (3 V/m) did not induce any significant DNA damage, but a slight increase was observed for extreme stress levels (76.4 V/m). On the other hand, the results indicate that, at both, low and high electric field intensity UMTS (Universal Mobile Telecommunications System) signal could be statistically related to DNA damage in-vitro. Nevertheless, further experiments are required, increasing the statistical number of samples and recruiting more DNA damage endpoints before conclusive statements are drawn.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Comet Assay
DNA Damage / radiation effects
Electromagnetic Fields*
Humans
Jurkat Cells
T-Lymphocytes / cytology
T-Lymphocytes / metabolism
T-Lymphocytes / radiation effects
Temperature