The Problem of Carbapenemase-Producing-Carbapenem-Resistant-Enterobacteriaceae Detection

J Clin Microbiol. 2016 Mar;54(3):529-34. doi: 10.1128/JCM.02771-15. Epub 2016 Jan 6.

Abstract

The emergence and spread of carbapenemase-producing carbapenem-resistant Enterobacteriaceae (CP-CRE) are a significant clinical and public health concern. Reliable detection of CP-CRE is the first step in combating this problem. There are both phenotypic and molecular methods available for CP-CRE detection. There is no single detection method that is ideal for all situations.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Bacterial Proteins / analysis*
  • Bacteriological Techniques / methods*
  • Carbapenems / pharmacology*
  • Diagnostic Tests, Routine / methods
  • Enterobacteriaceae / enzymology*
  • Enterobacteriaceae / isolation & purification
  • Enterobacteriaceae Infections / diagnosis*
  • Enterobacteriaceae Infections / microbiology
  • Humans
  • beta-Lactam Resistance*
  • beta-Lactamases / analysis*

Substances

  • Anti-Bacterial Agents
  • Bacterial Proteins
  • Carbapenems
  • beta-Lactamases
  • carbapenemase