Individualized real-time clinical decision support to monitor cardiac loading during venoarterial ECMO

J Transl Med. 2016 Jan 6;14:4. doi: 10.1186/s12967-015-0760-1.


Veno-arterial extracoporeal membrane oxygenation (VA ECMO) is increasingly used for acute and refractory cardiogenic shock. Yet, in clinical practice, monitoring of cardiac loading conditions during VA ECMO can be cumbersome. To this end, we illustrate the validity and clinical applicability of a real-time cardiovascular computer simulation, which allows to integrate hemodynamics, cardiac dimensions and the corresponding degree of VA ECMO support and ventricular loading in individual patients over time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Computer Simulation
  • Computer Systems*
  • Decision Support Systems, Clinical*
  • Diastole
  • Electrocardiography
  • Extracorporeal Membrane Oxygenation*
  • Heart / physiopathology*
  • Heart Ventricles / physiopathology
  • Hemodynamics
  • Humans
  • Monitoring, Physiologic*
  • Precision Medicine*