Clinical evaluation of an after-pediculicide nit removal system

Int J Dermatol. 1989 Sep;28(7):468-70. doi: 10.1111/j.1365-4362.1989.tb02511.x.


A significant problem in the management of pediculosis is the removal of nits from the hair after pediculicide treatment. This study describes use of a nit removal system incorporating a cream rinse containing formic acid that loosens the bond between the nit and hair. Twenty-four children with pediculosis capitis, age 4 to 12 years, were evaluated. Sections of hair with equivalent numbers of nits were identified as control or test sites. Combining for 5 minutes after use of the formic acid rinse removed 93.5% of nits compared with a 27.6% reduction in the control section (p less than 0.0001). These results demonstrate that use of this nit removal system greatly facilitates nit removal.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Animals
  • Child
  • Child, Preschool
  • Clinical Trials as Topic
  • Female
  • Formates / pharmacology*
  • Humans
  • Lice Infestations / drug therapy*
  • Male
  • Ovum / drug effects*
  • Pediculus / growth & development*
  • Pyrethrins / pharmacology
  • Pyrethrins / therapeutic use
  • Soaps


  • Formates
  • Pyrethrins
  • Soaps
  • formic acid