Abstract
Strain-specific circulating immunoglobulin G and/or M was detected by enzyme-linked immunosorbent assay and immunofluorescence test by using Formol-treated suspensions of Gardnerella vaginalis from 28 women with overt vaginitis but only three symptom-free subjects among 43 otherwise healthy women found to be colonized by G. vaginalis. Analogous but less stringent strain specificity patterns were elicited by immunization of BALB/c mice.
MeSH terms
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Adult
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Animals
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Antibodies, Bacterial / biosynthesis*
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Antibody Specificity
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Enzyme-Linked Immunosorbent Assay
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Female
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Fluorescent Antibody Technique
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Gardnerella vaginalis / immunology*
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Haemophilus / immunology*
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Haemophilus Infections / immunology*
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Humans
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Immunoglobulin G / biosynthesis
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Immunoglobulin M / biosynthesis
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Mice
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Mice, Inbred BALB C
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Vaginitis / immunology*
Substances
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Antibodies, Bacterial
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Immunoglobulin G
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Immunoglobulin M