Epidural anesthesia for cesarean section for pregnant women with rheumatic heart disease and mitral stenosis

Arch Gynecol Obstet. 2016 Jul;294(1):103-8. doi: 10.1007/s00404-015-4003-8. Epub 2016 Jan 7.

Abstract

Purpose: Pregnancy increases stress on the circulation of parturient with mitral stenosis secondary to rheumatic heart disease and increases the risk of peripartum heart failure, especially during delivery. This study investigated the epidural anesthesia management for cesarean section in pregnant women with rheumatic heart disease and mitral stenosis.

Methods: 48 parturients with rheumatic heart disease and mitral stenosis that had cesarean section deliveries with epidural anesthesia in the Union Hospital, Fujian Medical University (Fuzhou, China) from Jan 2002 to Dec 2012 were retrospectively analyzed. Heart rate (HR), systolic arterial pressure (SAP), diastolic arterial pressure (DAP), mean arterial pressure (MAP), central venous pressure (CVP), fluid intake volume and fluid output volume (blood loss + urine volume) were analyzed.

Results: Medication included digitalis drugs for heart failure or potential heart failure, digoxin and furosemide for chronic congestive heart failure and beta blockers for arrhythmia. Frequent premature ventricular contractions were treated with lidocaine and propafenone. Dexamethasone was administered when heart failure occurred during less than 37 weeks gestation. HR, SAP, DAP, MAP and CVP were significantly increased at the time of delivery. The fluid intake volume was more elevated in the NYHA III-IV group of parturients than the NYHA I-II group, while fluid output volume was less. All parturients survived.

Conclusions: Epidural anesthesia was applied successfully for cesarean sections for parturients with rheumatic heart disease and mitral stenosis.

Keywords: Cesarean section; Epidural anesthesia; Pregnancy; Rheumatic heart disease.

MeSH terms

  • Adult
  • Anesthesia, Epidural / methods*
  • Anesthesia, Obstetrical / methods*
  • Anti-Arrhythmia Agents / administration & dosage
  • Cesarean Section*
  • China
  • Digoxin / administration & dosage
  • Diuretics / administration & dosage
  • Female
  • Furosemide / administration & dosage
  • Gestational Age
  • Heart Failure / drug therapy
  • Heart Failure / prevention & control
  • Humans
  • Mitral Valve Stenosis / complications
  • Mitral Valve Stenosis / physiopathology
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / physiopathology
  • Pregnancy Outcome
  • Pregnant Women
  • Retrospective Studies
  • Rheumatic Heart Disease / complications
  • Rheumatic Heart Disease / physiopathology
  • Young Adult

Substances

  • Anti-Arrhythmia Agents
  • Diuretics
  • Digoxin
  • Furosemide