Fatigue and Vitamin D Status in Iranian Female Nurses

Glob J Health Sci. 2015 Nov 17;8(6):196-202. doi: 10.5539/gjhs.v8n6p196.


Introduction: Given that nurses are among professions with frequent ‎problems of fatigue, and given the nature of their profession that ‎provides little exposure to sunlight and the subsequent deficiency of vitamin D, the ‎present study examined the relation between fatigue and circulating vitamin D levels ‎in female nurses working in Shahid Beheshti Hospital, Kashan, Iran in 2013. ‎

Material & methods: This cross-sectional study was conducted in 200 female nurses working in Shahid Beheshti Hospital. To measure fatigue, fatigue questionnaire containing 9 ‎questions eliciting the subject's feeling in scales of 1 to 7, getting a possible score of 9 to ‎‎63, and Visual Analogue Scale ‎in which nurses specified their fatigue in a band of zero to 10 were used. ‎The 25-hydroxyvitamin D, which is the most important vitamin D metabolite, also was determined. The data was analyzed by SPSS-16. The Pearson's correlation of coefficients, t-test, and multiple regression analysis were used in this study.‎

Results: The mean fatigue score of nurses was 38.76±12.66 in questionnaire and 5.73±2.12 in Visual Analog Scale. The 89 per cent of nurses suffered from vitamin D deficiency, ‎‎9.5 percent of them had normal level and 1.5 per cent had toxicity level of vitamin D.‎ There was a significant relationship between vitamin D level and fatigue scores (P<0.0001), and visual fatigue scores (P<0.0001). According to multivariate regression analysis, vitamin D level accounted for 13 per cent ‎of the fatigue based on data on questionnaire and‎ ‎18.6 per cent of ‎fatigue according to Visual Analog Scale. ‎

Conclusion: High prevalence of fatigue among nurses could be attributed to vitamin D ‎deficiency.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Comorbidity
  • Cross-Sectional Studies
  • Fatigue / blood*
  • Fatigue / epidemiology*
  • Female
  • Humans
  • Iran / epidemiology
  • Middle Aged
  • Nurses / statistics & numerical data*
  • Prevalence
  • Vitamin D / blood*
  • Vitamin D Deficiency / blood*
  • Vitamin D Deficiency / epidemiology*
  • Young Adult


  • Vitamin D