[Onychocola canadensis Sigler in onychomycosis : A new dermatophyte-like mould in Germany]

Hautarzt. 2016 Sep;67(9):739-49. doi: 10.1007/s00105-015-3755-1.
[Article in German]


Moulds or non-dermatophyte moulds (NDM) are being increasingly isolated as causative agent of onychomycoses. Known causes of a NDM-OM are Scopulariopsis brevicaulis, Fusarium, Aspergillus, Acremonium, Neoscytalidium dimidiatum, Arthrographis kalrae, and Chaetomium. In this article, 5 patients with suspected nail infection due to Onychocola canadensis are reported for the first time in Germany. Systemic antifungal agents are not considered to be effective in NDM onychomycosis. In individual cases, however, terbinafine seems to be effective in Onychocola canadensis infection of the nails. Treatment of choice represents, however, nontraumatic nail avulsion using 40 % urea ointment followed by antifungal nail lacquer with ciclopirox olamine or amorolfine.

Keywords: Ciclopirox olamine; DNA-Sequencing; Nail avulsion; Onychomycosis; Terbinafine.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antifungal Agents / therapeutic use
  • Communicable Diseases, Emerging / diagnosis
  • Communicable Diseases, Emerging / drug therapy
  • Communicable Diseases, Emerging / microbiology
  • Female
  • Germany
  • Humans
  • Male
  • Middle Aged
  • Naphthalenes / therapeutic use*
  • Onychomycosis / diagnosis*
  • Onychomycosis / drug therapy*
  • Onychomycosis / microbiology
  • Onygenales / isolation & purification*
  • Terbinafine
  • Treatment Outcome


  • Antifungal Agents
  • Naphthalenes
  • Terbinafine