Experience in 300 cases of CT-directed stereotactic surgery for lesion biopsy and aspiration of haematoma

Br J Neurosurg. 1989;3(3):321-5. doi: 10.3109/02688698909002810.


Despite advances in imaging of the brain, an accurate diagnosis of brain lesions requires tissue sampling and histological verification. A series of CT-directed procedures has been performed in 300 patients with deep sited, multiple, diffuse, extensive, small or inflammatory lesions, brain stem haematomas and tumours presenting with epilepsy. A positive diagnosis was obtained in 271 cases (92.8%), no diagnosis in 21 cases (7.2%). Therapeutic results were also obtained in eight cases (2.7%) of brain stem haematoma aspiration. Complications occurred in 14 cases (4.7%) including one death (0.3%). Because of the importance of an accurate diagnosis in order to avoid inappropriate therapy, together with the relative safety of the technique, CT-directed stereotactic biopsy should be considered in all patients harbouring deep seated, multiple, diffuse, small or inflammatory brain lesions.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Biopsy, Needle / methods
  • Brain Neoplasms / pathology*
  • Brain Neoplasms / therapy
  • Cerebral Hemorrhage / pathology*
  • Cerebral Hemorrhage / therapy
  • Child
  • Female
  • Humans
  • Male
  • Middle Aged
  • Stereotaxic Techniques*
  • Suction / methods
  • Tomography, X-Ray Computed