Evaluation of the effectiveness of a chamomile (Matricaria chamomilla) and linseed (Linum usitatissimum) saliva substitute in the relief of xerostomia in elders

Gerodontology. 2017 Mar;34(1):42-48. doi: 10.1111/ger.12220. Epub 2016 Jan 14.

Abstract

Objective: The aim of this study was to determine the efficacy of a chamomile (Matricaria chamomilla) and linseed (Linum usitatissimum) saliva substitute in the relief of xerostomia in older participants.

Background: In elders, xerostomia is a permanent and progressive condition that significantly affects their quality of life. The treatment for progressive xerostomia is currently restricted to palliative measures, and saliva substitutes are indicated. A lack of evidence on the effectiveness of the saliva substitutes in the relief of symptoms of xerostomia has been reported.

Materials and methods: Seventy-four elderly participants presenting xerostomia of diverse origin were selected. Herbal saliva substitute and carboxymethyl cellulose conventional saliva substitute were tested using a double-blind, randomised, cross-sectional clinical trial.

Results: Every participant of the study exhibited dry mouth sensation. A sensation of thick saliva was described in 59.5% of the participants. The need for liquid intake to swallow food, the sensation of difficulty in swallowing and the burning sensation in the tongue were observed in 54.1, 56.8 and 27.0% of the participants, respectively. The most prevalent diseases were hypertension, depressive symptoms and arthritis. Results of the clinical tests showed that the herbal saliva substitute produced a greater relief of dry mouth symptoms, thick saliva sensation and the sensation of difficulty in swallowing than the conventional substitute (Wilcoxon test p < 0.05).

Conclusions: New chamomile- and linseed-based saliva substitute was effective in relieving xerostomia symptoms in older participants of this study.

Keywords: chamomile; elderly; linseed; xerostomia.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Chamomile*
  • Double-Blind Method
  • Female
  • Flax*
  • Herbal Medicine / methods*
  • Humans
  • Male
  • Phytotherapy / mortality*
  • Plant Extracts / therapeutic use*
  • Saliva, Artificial / therapeutic use*
  • Salivation / drug effects
  • Xerostomia / drug therapy*

Substances

  • Plant Extracts
  • Saliva, Artificial