Detection and Prevalence of Penicillin-Susceptible Staphylococcus aureus in the United States in 2013

J Clin Microbiol. 2016 Mar;54(3):812-4. doi: 10.1128/JCM.03109-15. Epub 2016 Jan 13.

Abstract

Using blaZ PCR as the "gold standard," the sensitivities of CLSI penicillin zone edge and nitrocefin-based tests for β-lactamase production in Staphylococcus aureus were 64.5% and 35.5%, respectively, with specificity of 99.8% for both methods. In 2013, 13.5% of 3,083 S. aureus isolates from 31 U.S. centers were penicillin susceptible.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Genes, Bacterial
  • Humans
  • Methicillin-Resistant Staphylococcus aureus / drug effects
  • Microbial Sensitivity Tests
  • Penicillin Resistance*
  • Penicillins / pharmacology*
  • Prevalence
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / drug effects*
  • United States / epidemiology

Substances

  • Penicillins