Published GMO studies find no evidence of harm when corrected for multiple comparisons

Crit Rev Biotechnol. 2017 Mar;37(2):213-217. doi: 10.3109/07388551.2015.1130684. Epub 2016 Jan 14.


A number of widely debated research articles claiming possible technology-related health concerns have influenced the public opinion on genetically modified food safety. We performed a statistical reanalysis and review of experimental data presented in some of these studies and found that quite often in contradiction with the authors' conclusions the data actually provides weak evidence of harm that cannot be differentiated from chance. In our opinion the problem of statistically unaccounted multiple comparisons has led to some of the most cited anti-genetically modified organism health claims in history. We hope this analysis puts the original results of these studies into proper context.

Keywords: GMO; Genetic engineering; genetic modification; health; safety; statistics; transgenic.

Publication types

  • Review

MeSH terms

  • Animals
  • Data Interpretation, Statistical
  • Humans
  • Organisms, Genetically Modified*
  • Toxicity Tests / statistics & numerical data*