A fast field-cycling device for high-resolution NMR: Design and application to spin relaxation and hyperpolarization experiments

Alexey S Kiryutin; Andrey N Pravdivtsev; Konstantin L Ivanov; Yuri A Grishin; Hans-Martin Vieth; Alexandra V Yurkovskaya

doi:10.1016/j.jmr.2015.11.017

A fast field-cycling device for high-resolution NMR: Design and application to spin relaxation and hyperpolarization experiments

J Magn Reson. 2016 Feb:263:79-91. doi: 10.1016/j.jmr.2015.11.017. Epub 2015 Dec 29.

Authors

Alexey S Kiryutin¹, Andrey N Pravdivtsev², Konstantin L Ivanov², Yuri A Grishin³, Hans-Martin Vieth⁴, Alexandra V Yurkovskaya²

Affiliations

¹ International Tomography Center, Siberian Branch of the Russian Academy of Science, Institutskaya 3a, Novosibirsk 630090, Russia; Novosibirsk State University, Pirogova 2, Novosibirsk 630090, Russia. Electronic address: kalex@tomo.nsc.ru.
² International Tomography Center, Siberian Branch of the Russian Academy of Science, Institutskaya 3a, Novosibirsk 630090, Russia; Novosibirsk State University, Pirogova 2, Novosibirsk 630090, Russia.
³ Institute of Chemical Kinetics and Combustion, Siberian Branch of the Russian Academy of Science, Institutskaya 3, Novosibirsk 630090, Russia.
⁴ International Tomography Center, Siberian Branch of the Russian Academy of Science, Institutskaya 3a, Novosibirsk 630090, Russia; Institut für Experimentalphysik, Freie Universität Berlin, Arnimallee 14, D-14195 Berlin, Germany. Electronic address: hmvieth@zedat.fu-berlin.de.

PMID: 26773525
DOI: 10.1016/j.jmr.2015.11.017

Abstract

A device for performing fast magnetic field-cycling NMR experiments is described. A key feature of this setup is that it combines fast switching of the external magnetic field and high-resolution NMR detection. The field-cycling method is based on precise mechanical positioning of the NMR probe with the mounted sample in the inhomogeneous fringe field of the spectrometer magnet. The device enables field variation over several decades (from 100μT up to 7T) within less than 0.3s; progress in NMR probe design provides NMR linewidths of about 10(-3)ppm. The experimental method is very versatile and enables site-specific studies of spin relaxation (NMRD, LLSs) and spin hyperpolarization (DNP, CIDNP, and SABRE) at variable magnetic field and at variable temperature. Experimental examples of such studies are demonstrated; advantages of the experimental method are described and existing challenges in the field are outlined.

Keywords: Fast field-cycling; NMR instrumentation; Spin hyperpolarization; Spin relaxation.

Publication types

Research Support, Non-U.S. Gov't