Bilateral Idiopathic Solitary Granuloma of the Uveal Tract: Diagnosis and Treatment

Int J Ophthalmic Pathol. 2015;4(4):166. doi: 10.4172/2324-8599.1000166. Epub 2015 Oct 15.


We present a case of sequential bilateral idiopathic solitary granuloma of the uveal tract in a 51 year-old woman, who underwent enucleation in one eye due to complications of this condition, but was then successfully treated in the contralateral eye with anti-tumor necrosis-alpha therapy followed shortly by intraocular steroids and a steroid-releasing implant. Her visual acuity at its worst was 20/200 due to vitreous haze and cystoid macular edema, but then stabilized after successful treatment with a final visual acuity of 20/25 in her only seeing eye at 1 year follow-up. This represents the first known biopsy-proven case of bilateral idiopathic solitary granuloma, which additionally, has responded favorably to treatment.

Keywords: Ciliary body granuloma; Infliximab; Necrotizing granulomatous disease; Uveitis.