Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Jan 19;13(1):e1001946.
doi: 10.1371/journal.pmed.1001946. eCollection 2016 Jan.

Sharing Individual Participant Data (IPD) Within the Context of the Trial Reporting System (TRS)

Free PMC article

Sharing Individual Participant Data (IPD) Within the Context of the Trial Reporting System (TRS)

Deborah A Zarin et al. PLoS Med. .
Free PMC article


Deborah Zarin and Tony Tse of ClinicalTrials.Gov consider how sharing individual participant data can and cannot help improve the reporting of clinical trials.

Conflict of interest statement

We have read the journal's policy and have the following conflicts: DAZ is Director and TT is an Analyst for


Fig 1
Fig 1. Schematic depicting information granularity for different types of data [12].
Fig 2
Fig 2. Schematic depicting the functions of the three key components of the TRS.
Fig 3
Fig 3. Schematic depicting as an “information scaffold” using the record unique identifier (NCT number) to link to various online resources.

Similar articles

See all similar articles

Cited by 12 articles

See all "Cited by" articles


    1. Institute of Medicine (2015) Sharing clinical trial data: maximizing benefits, minimizing risks Washington DC: The National Academies Press.
    1. Drazen JM (2015) Sharing individual patient data from clinical trials. N Engl J Med 372: 201–202. 10.1056/NEJMp1415160 - DOI - PubMed
    1. Data Availability Policy. PLoS Med; 2016. [cited 2016 Jan 6].
    1. Eichler HG, Abadie E, Breckenridge A, Leufkens H, Rasi G (2012) Open clinical trial data for all? A view from regulators. PLoS Med 9: e1001202 10.1371/journal.pmed.1001202 - DOI - PMC - PubMed
    1. Krumholz HM, Peterson ED (2014) Open access to clinical trials data. JAMA 312: 1002–1003. 10.1001/jama.2014.9647 - DOI - PubMed

Publication types

MeSH terms