Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016;12(5):493-500.
doi: 10.1586/1744666X.2016.1144472. Epub 2016 Feb 24.

Etanercept for the Treatment of Non-Radiographic Axial Spondyloarthritis

Affiliations
Review

Etanercept for the Treatment of Non-Radiographic Axial Spondyloarthritis

Valeria Rios Rodriguez et al. Expert Rev Clin Immunol. .

Abstract

Presently, tumor necrosis factor α antagonist therapy is the only effective alternative treatment to nonsteroidal anti-inflammatory drugs for the entire spectrum of axial spondyloarthritis, including non-radiographic and radiographic (=ankylosing spondylitis) forms. Recently, etanercept has been approved by the European Medicines Agency for the treatment of non-radiographic axial spondyloarthritis, increasing the number of available treatment options for this indication. The latest data on etanercept concerning clinical efficacy and safety in short-term and long-term treatment of patients with non-radiographic axial spondyloarthritis who do not respond to the first-line therapy with non-steroidal anti-inflammatory drugs suggests good efficacy and safety profiles similar to that observed previously in ankylosing spondylitis. This article reviews recent data on the efficacy and safety of etanercept and is focused on the treatment of non-radiographic axial spondyloarthritis. This article will also discuss the role of etanercept in the context of current and developing treatment options.

Keywords: Axial spondyloarthritis; ankylosing spondylitis; etanercept; non-radiographic axial spondyloarthritis; treatment; tumor necrosis factor (TNF) blockers.

Similar articles

See all similar articles

MeSH terms

LinkOut - more resources

Feedback