Tissue-Specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans

J Clin Endocrinol Metab. 2016 Apr;101(4):1455-68. doi: 10.1210/jc.2015-3336. Epub 2016 Jan 20.

Abstract

Integrative multiomics analyses of adipose and muscle tissue transcripts, S, and genotypes revealed novel genetic regulatory mechanisms of insulin resistance in African Americans.

Publication types

  • Comparative Study

MeSH terms

  • Adipose Tissue / metabolism*
  • Adolescent
  • Adult
  • African Americans / genetics*
  • Biomarkers / metabolism*
  • Cross-Sectional Studies
  • European Continental Ancestry Group / genetics
  • Female
  • Gene Expression Regulation*
  • Glucose Tolerance Test
  • High-Throughput Nucleotide Sequencing
  • Humans
  • Insulin Resistance / genetics*
  • Male
  • Middle Aged
  • Muscle, Skeletal / metabolism*
  • Young Adult

Substances

  • Biomarkers