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Review
. 2016 May 15;79:901-13.
doi: 10.1016/j.bios.2016.01.033. Epub 2016 Jan 13.

Applying the Miniaturization Technologies for Biosensor Design

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Review

Applying the Miniaturization Technologies for Biosensor Design

Burak Derkus. Biosens Bioelectron. .

Abstract

Microengineering technologies give us some opportunities in developing high-tech sensing systems that operate with low volumes of samples, integrates one or more laboratory functions on a single substrate, and enables automation. These millimetric sized devices can be produced for only a few dollars, which makes them promising candidates for mass-production. Besides electron beam lithography, stencil lithography, nano-imprint lithography or dip pen lithography, basic photolithography is the technique which is extensively used for the design of microengineered sensing systems. This technique has some advantages such as easy-to-manufacture, do not require expensive instrumentation, and allow creation of lower micron-sized patterns. In this review, it has been focused on three different type of microengineered sensing devices which are developed using micro/nano-patterning techniques, microfluidic technology, and microelectromechanics system based technology.

Keywords: MEMs; Microfluidics; Micropatterning; Microtechnology; Miniaturization; Nanopatterning; Nanotechnology.

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