Transitional Cell Carcinoma in the Pediatric Patient: A Review of the Literature

Stephanie Chu; Jennifer Singer

doi:10.1016/j.urology.2015.12.032

Transitional Cell Carcinoma in the Pediatric Patient: A Review of the Literature

Urology. 2016 May:91:175-9. doi: 10.1016/j.urology.2015.12.032. Epub 2016 Jan 21.

Authors

Stephanie Chu¹, Jennifer Singer²

Affiliations

¹ Department of Urology, University of California, Los Angeles, Los Angeles, CA. Electronic address: sdchu@mednet.ucla.edu.
² Department of Urology, University of California, Los Angeles, Los Angeles, CA.

PMID: 26802795
DOI: 10.1016/j.urology.2015.12.032

Abstract

Transitional cell carcinoma (TCC) is extremely rare in children, with fewer than 30 cases reported in patients under 10 years old. It is thought that pediatric TCC is fundamentally different than TCC in adults; however, there are no specific guidelines for management or surveillance. Furthermore, the addition of papillary urothelial neoplasm of low malignant potential as a diagnosis has changed the management of lesions previously considered malignant. This review aims to investigate the difference between TCC in adults and children, to report current strategies for management of pediatric TCC, and to analyze the effects of the new grading system.

Publication types

Case Reports
Review

MeSH terms

Carcinoma, Transitional Cell* / diagnosis
Carcinoma, Transitional Cell* / therapy
Child
Female
Humans
Kidney Neoplasms* / diagnosis
Kidney Neoplasms* / therapy
Male
Neoplasm Grading