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doi: 10.1016/j.devcel.2016.01.006.
A Wacky Bridge to mTORC1 Dimerization
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- PMID: 26812011
- DOI: 10.1016/j.devcel.2016.01.006
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A Wacky Bridge to mTORC1 Dimerization
Dev Cell.
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Free article
Abstract
The activity of the mTORC1 protein complex depends on multiple metabolic inputs that regulate dimerization, recruitment to the lysosome, and activation. In this issue of Developmental Cell, David-Morrison et al. (2016) show that the Drosophila protein Wacky and its mammalian counterpart WAC act as adaptors in the process of mTORC1 dimerization.
Copyright © 2016 Elsevier Inc. All rights reserved.
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