Sulfasalazine toxic reactions. Hepatitis, fever, and skin rash with hypocomplementemia and immune complexes

JAMA. 1978 Jun 16;239(24):2590-1. doi: 10.1001/jama.239.24.2590.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antigen-Antibody Complex*
  • Chemical and Drug Induced Liver Injury / etiology*
  • Complement System Proteins* / analysis
  • Crohn Disease / drug therapy
  • Drug Hypersensitivity* / immunology
  • Fever / chemically induced
  • Humans
  • Lymphocyte Activation
  • Male
  • Pruritus / chemically induced*
  • Sulfasalazine / adverse effects*
  • Sulfasalazine / therapeutic use

Substances

  • Antigen-Antibody Complex
  • Sulfasalazine
  • Complement System Proteins