Draft Genome of Multidrug-Resistant Klebsiella pneumoniae 223/14 Carrying KPC-6, Isolated from a General Hospital in Malaysia

J Genomics. 2015 Nov 16;3:97-8. doi: 10.7150/jgen.13910. eCollection 2015.

Abstract

We performed whole genome sequencing on a clinical multidrug-resistant Klebsiella pneumoniae strain 223/14. Investigation into its draft genome revealed the presence of KPC-6 variant, suggesting carbapenemase is present in this isolate. We found a plasmid-borne KPC gene (882 bp) inserted between two transposase genes in the genome of K. pneumoniae 223/14.

Keywords: Klebsiella pneumoniae Carbapenemase (KPC); multidrug resistance; whole genome sequencing.