Ultrasound Evaluation of the Combined Effects of Thoracolumbar Fascia Injury and Movement Restriction in a Porcine Model

PLoS One. 2016 Jan 28;11(1):e0147393. doi: 10.1371/journal.pone.0147393. eCollection 2016.

Abstract

The persistence of back pain following acute back "sprains" is a serious public health problem with poorly understood pathophysiology. The recent finding that human subjects with chronic low back pain (LBP) have increased thickness and decreased mobility of the thoracolumbar fascia measured with ultrasound suggest that the fasciae of the back may be involved in LBP pathophysiology. This study used a porcine model to test the hypothesis that similar ultrasound findings can be produced experimentally in a porcine model by combining a local injury of fascia with movement restriction using a "hobble" device linking one foot to a chest harness for 8 weeks. Ultrasound measurements of thoracolumbar fascia thickness and shear plane mobility (shear strain) during passive hip flexion were made at the 8 week time point on the non-intervention side (injury and/or hobble). Injury alone caused both an increase in fascia thickness (p = .007) and a decrease in fascia shear strain on the non-injured side (p = .027). Movement restriction alone did not change fascia thickness but did decrease shear strain on the non-hobble side (p = .024). The combination of injury plus movement restriction had additive effects on reducing fascia mobility with a 52% reduction in shear strain compared with controls and a 28% reduction compared to movement restriction alone. These results suggest that a back injury involving fascia, even when healed, can affect the relative mobility of fascia layers away from the injured area, especially when movement is also restricted.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Calcitonin Gene-Related Peptide / metabolism
  • Fascia / diagnostic imaging
  • Fascia / injuries
  • Gait
  • Low Back Pain / diagnostic imaging*
  • Low Back Pain / metabolism
  • Male
  • Range of Motion, Articular
  • Spinal Cord / diagnostic imaging
  • Spinal Cord / metabolism
  • Spinal Cord / pathology
  • Substance P / metabolism
  • Sus scrofa
  • Ultrasonography

Substances

  • Substance P
  • Calcitonin Gene-Related Peptide