The effects of smoking on dry eye parameters in healthy women

Cutan Ocul Toxicol. 2017 Mar;36(1):1-4. doi: 10.3109/15569527.2015.1136828. Epub 2016 Jan 28.


Aim: To investigate the effects of chronic smoking on dry eye parameters.

Methods: Ocular surface disease index (OSDI) and tear function tests such as Schirmer's test, tear break-up-time (TBUT) test and impression cytology of 63 female chronic smokers and 40 age-matched female non-smokers were analyzed statistically.

Results: The mean OSDI scores, Schirmer test results and TBUT levels were 35.85 ± 24.01 point, 14.25 ± 5.94 mm and 5.17 ± 2.85 s in chronic smokers and 15.20 ± 12.93 point, 15.48 ± 7.01 mm and 10.03 ± 3.44 s in non-smokers, respectively. Differences in OSDI scores, TBUT levels and impression cytology grades among the chronic smokers and non-smokers were statistically significant.

Conclusion: Smoking behavior seems to affect the dry eye parameters negatively.

Keywords: Cigarette; dry eye; impression cytology; smoking; tear function tests.

MeSH terms

  • Adult
  • Case-Control Studies
  • Conjunctiva / pathology
  • Diagnostic Techniques, Ophthalmological
  • Dry Eye Syndromes / diagnosis
  • Dry Eye Syndromes / etiology*
  • Female
  • Humans
  • Middle Aged
  • Smoking / adverse effects*
  • Surveys and Questionnaires