Monoterpenoid Bisindole Alkaloids

Alkaloids Chem Biol. 2016:76:259-310. doi: 10.1016/bs.alkal.2015.09.001. Epub 2015 Oct 21.

Abstract

This chapter covers the literature on bisindole alkaloids consisting of monoterpenoid indoles, published up to June 2015. Bisindole alkaloids isolated from plants belonging to the families Apocynaceae and Loganiaceae, including Iboga-vobasine type, Aspidosperma-Aspidosperma type, eburnan-Aspidosperma type, Strychnos-Strychnos type, macroline-macroline type, and so on, are described. Some recent syntheses of monoterpenoid bisindole alkaloids are outlined as well.

Keywords: Alkaloid; Bisindole; Monoterpene; Structure elucidation; Total synthesis.

Publication types

  • Review

MeSH terms

  • Aspidosperma / chemistry
  • Indole Alkaloids / metabolism
  • Secologanin Tryptamine Alkaloids / metabolism*
  • Tabernaemontana / chemistry

Substances

  • Indole Alkaloids
  • Secologanin Tryptamine Alkaloids
  • eburnan
  • vobasine