Evaluation of Intraocular Inflammation with Laser Flare Photometry in Behçet Uveitis

Ocul Immunol Inflamm. 2017 Feb;25(1):41-45. doi: 10.3109/09273948.2015.1108444. Epub 2016 Jan 30.

Abstract

Purpose: To evaluate the association between intraocular inflammation and laser flare photometry measurements in Behçet disease.

Methods: In total, 45 patients were included in the study. The retrospective chart reviews of patients were performed. The flare levels were compared with the grade of anterior chamber cells, the presence of vitreous cells, the complications of uveitis, and fluorescein angiography scores.

Results: The attack group had higher flare intensity; the flare levels were higher in both groups compared with the values of healthy controls. The flare levels were related to the grade of the anterior chamber cells, the presence of vitreous cells and the fluorescein angiography scores. Patients with optic atrophy and/or maculopathy also had higher values. Higher flare values were correlated with poor vision.

Conclusions: Laser flare photometry may reduce the necessity of fluorescein angiography in monitoring subclinical inflammation and may be an indicator of posterior segment activity when fluorescein angiography is not applicable.

Keywords: Behçet disease; fluorescein angiography; intraocular inflammation; laser flare photometry; uveitis.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Anterior Chamber / pathology*
  • Behcet Syndrome / diagnosis*
  • Blood-Aqueous Barrier
  • Cell Count
  • Female
  • Fluorescein Angiography
  • Humans
  • Male
  • Photometry / methods*
  • Retrospective Studies
  • Uveitis, Anterior / diagnosis*
  • Visual Acuity / physiology