Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Jun;31:16-24.
doi: 10.1016/j.mib.2015.12.010. Epub 2016 Jan 30.

Mimivirus Inaugurated in the 21st Century the Beginning of a Reclassification of Viruses

Affiliations
Free article
Review

Mimivirus Inaugurated in the 21st Century the Beginning of a Reclassification of Viruses

Vikas Sharma et al. Curr Opin Microbiol. .
Free article

Abstract

Mimivirus and other giant viruses are visible by light microscopy and bona fide microbes that differ from other viruses and from cells that have a ribosome. They can be defined by: giant virion and genome sizes; their complexity, with the presence of DNA and mRNAs and dozens or hundreds of proteins in virions; the presence of translation-associated components; a mobilome including (pro)virophages (and a defence mechanism, named MIMIVIRE, against them) and transpovirons; their monophyly; the presence of the most archaic protein motifs they share with cellular organisms but not other viruses; a broader host range than other viruses. These features show that giant viruses are specific, autonomous, biological entities that warrant the creation of a new branch of microbes.

Similar articles

See all similar articles

Cited by 14 articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback