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. 2016 Aug;265:54-60.
doi: 10.1016/j.forsciint.2016.01.006. Epub 2016 Jan 16.

A Study to Model the Post-Mortem Stability of 4-MMC, MDMA and BZP in Putrefying Remains

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A Study to Model the Post-Mortem Stability of 4-MMC, MDMA and BZP in Putrefying Remains

Daniel S Wenholz et al. Forensic Sci Int. .

Abstract

There is currently limited data available on the stabilities of the three stimulants 4-methylmethcathinone (4-MMC), 3,4-methylenedioxymethamphetamine (MDMA) and N-benzylpiperazine (BZP) in a putrefying matrix. A Gas Chromatography Mass Spectrometry (GC-MS) method to determine the concentration of the three drugs in putrefying porcine liver over a three month period was developed and validated. Both 4-MMC and BZP were found to be unstable, becoming undetectable and having an average recovery of 52% respectively after one month at ambient room temperature (20°C). MDMA was found to be moderately stable, with an average recovery of 74% after three months at room temperature. This study indicated that the putrefaction process could have a significant impact on concentrations of 4-MMC and BZP in post-mortem cases involving putrefied remains.

Keywords: 3,4-methylenedioxymethamphetamine; 4-methylmethcathinone; N-benzylpiperazine; Putrefactive degradation.

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    Nowak K, Szpot P, Zawadzki M. Nowak K, et al. Forensic Toxicol. 2019;37(1):261-264. doi: 10.1007/s11419-018-0455-4. Epub 2018 Nov 19. Forensic Toxicol. 2019. PMID: 30636991 Free PMC article. No abstract available.

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