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Review
. 2016 Jun;12(2):192-8.
doi: 10.1007/s13181-016-0533-0.

Case Files of the University of Massachusetts Toxicology Fellowship: Does This Smoke Inhalation Victim Require Treatment with Cyanide Antidote?

Eike Hamad  1 , Kavita Babu  2 , Vikhyat S Bebarta  3   4   5
Affiliations
Review

Case Files of the University of Massachusetts Toxicology Fellowship: Does This Smoke Inhalation Victim Require Treatment with Cyanide Antidote?

Eike Hamad et al. J Med Toxicol. 2016 Jun.

Abstract

Cyanide toxicity is common after significant smoke inhalation. Two cases are presented that provide framework for the discussion of epidemiology, pathogenesis, presenting signs and symptoms, and treatment options of inhalational cyanide poisoning. An evidence-based algorithm is proposed that utilizes point-of-care testing to help physicians identify patients who benefit most from antidotal therapy.

Keywords: Cyanide; Fire; Hydroxocobalamin; Smoke inhalation; Sodium thiosulfate.

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Fig. 1
Fig. 1
Proposed diagnostic and treatment algorithm for inhalational cyanide toxicity after smoke exposure
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