A visco-poroelastic model of functional adaptation in bones reconstructed with bio-resorbable materials

Biomech Model Mechanobiol. 2016 Oct;15(5):1325-43. doi: 10.1007/s10237-016-0765-6. Epub 2016 Jan 30.

Abstract

In this paper, the phenomena of resorption and growth of bone tissue and resorption of the biomaterial inside a bicomponent system are studied by means of a numerical method based on finite elements. The material behavior is described by a poro-viscoelastic model with infiltrated voids. The mechanical stimulus that drives these processes is a linear combination of density of strain energy and viscous dissipation. The external excitation is represented by a bending load slowly variable with sinusoidal law characterized by different frequencies. Investigated aspects are the influence of the load frequency, of type of the stimulus and of the effective porosity on the time evolution of the mass densities of considered system.

Keywords: Bone functional adaptation; Continuum mixture model; Dissipation; Mechanical–biological coupling; Poro-viscoelasticity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptation, Physiological*
  • Biocompatible Materials / pharmacology*
  • Bone Density / drug effects
  • Cancellous Bone / drug effects
  • Cancellous Bone / physiology*
  • Computer Simulation
  • Elasticity*
  • Finite Element Analysis
  • Models, Biological*
  • Numerical Analysis, Computer-Assisted
  • Porosity
  • Stress, Mechanical
  • Viscosity

Substances

  • Biocompatible Materials