Glaucoma: the damage caused by pressure. XLVI Edward Jackson memorial lecture

Am J Ophthalmol. 1989 Nov 15;108(5):485-95. doi: 10.1016/0002-9394(89)90423-6.


I discuss the condition of chronic glaucoma in terms that make high intraocular pressure simply one of several risk factors instead of an integral part of the disease definition. I review some of the clinical observations that constitute a basis for this perspective and explore the immediate therapeutic implications of this manner of conceptualizing the disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Glaucoma / etiology
  • Glaucoma / pathology*
  • Glaucoma / therapy
  • Humans
  • Intraocular Pressure*
  • Optic Nerve / pathology
  • Prognosis
  • Risk Factors