Celiac disease and fibromyalgia: Is there an association?

Rev Esp Enferm Dig. 2016 Feb;108(2):107-8. doi: 10.17235/reed.2015.3992/2015.


It has been found that celiac disease (CD) and non-celiac gluten sensitivity (NCGS) have a high prevalence in fibromyalgia (FM) patients. NCGS is a relatively new entity characterized by gastrointestinal and extra-intestinal manifestations in the absence of CD or wheat allergy. It is different from CD because anti-transglutaminase (anti-tTG) or endomysial antibodies (IgA-EmA) are lacking and the intestinal mucosa is normal or with mild abnormalities as increased intraepithelial lymphocytes in the absence of villous atrophy.

Publication types

  • Letter

MeSH terms

  • Case-Control Studies
  • Celiac Disease / complications*
  • Celiac Disease / diagnosis*
  • Celiac Disease / epidemiology
  • Female
  • Fibromyalgia / complications*
  • Fibromyalgia / diagnosis
  • Humans
  • Risk Factors