Endometrial/ioid Stromal Tumors and Related Neoplasms of the Female Genital Tract

Esther Oliva; Patricia M Baker

doi:10.1016/j.path.2009.08.023

Endometrial/ioid Stromal Tumors and Related Neoplasms of the Female Genital Tract

Surg Pathol Clin. 2009 Dec;2(4):679-705. doi: 10.1016/j.path.2009.08.023. Epub 2009 Nov 29.

Authors

Esther Oliva¹, Patricia M Baker²

Affiliations

¹ Pathology Department (Warren 2), Massachusetts General Hospital/Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: eoliva@partners.org.
² University of Manitoba, 820 Sherbrook Street, Winnipeg, Manitoba, Canada R3A 1R9.

PMID: 26838775
DOI: 10.1016/j.path.2009.08.023

Abstract

Endometrial/ioid stromal tumors comprise a spectrum of mesenchymal neoplasms, ranging from benign to low-grade malignancy to undifferentiated sarcomas, which occur predominantly in the uterus but may rarely originate at extrauterine sites, most commonly in the ovary. These tumors and their morphologic variants are important to recognize as they often cause diagnostic difficulties. This review focuses on the diagnostic criteria and differential diagnosis, including the role of immunohistochemistry.

Keywords: Endometrial stromal nodule; Endometrial/ioid stromal variants; Female genital tract; Low-grade endometrial/ioid stromal sarcoma; Undifferentiated endometrial sarcoma; Uterine tumors resembling ovarian sex cord tumors.

Publication types

Review