Oral clomethiazole treatment for paediatric non-convulsive status epilepticus

Darshan Das; Sophia Varadkar; Krishna B Das

doi:10.1684/epd.2016.0795

Oral clomethiazole treatment for paediatric non-convulsive status epilepticus

Epileptic Disord. 2016 Mar;18(1):87-91. doi: 10.1684/epd.2016.0795.

Authors

Darshan Das¹, Sophia Varadkar², Krishna B Das³

Affiliations

¹ Young Epilepsy, Research, Lingfield, Kings College Hospital, Paediatric Neurosciences, London.
² Great Ormond Street Hospital, Paediatric Neurology, London, UK.
³ Young Epilepsy, Research, Lingfield, Great Ormond Street Hospital, Paediatric Neurology, London, UK.

PMID: 26842397
DOI: 10.1684/epd.2016.0795

Abstract

We report a retrospective case study of the use of clomethiazole for treatment of non-convulsive status epilepticus in a patient not responding to benzodiazepines, illustrated by EEG and video. Clomethiazole can be considered as a safe oral option for management of non-convulsive status epilepticus when conventional treatment has failed. [Published with video sequences online].

Keywords: non convulsive status epilepticus.

Publication types

Case Reports

MeSH terms

Adolescent
Benzodiazepines / therapeutic use*
Brain / physiopathology*
Chlormethiazole / administration & dosage
Chlormethiazole / therapeutic use*
Electroencephalography / methods
Humans
Male
Retrospective Studies
Status Epilepticus / diagnosis
Status Epilepticus / drug therapy*
Status Epilepticus / physiopathology
Treatment Outcome

Substances

Chlormethiazole
Benzodiazepines