Functional impairment and improvement in depression

J Clin Psychiatry. 2016 Jan;77(1):e35. doi: 10.4088/JCP.13097tx2c.


Functional impairment is inherent to depression, but frequently these impairments are more resistant to treatment than the actual symptoms of depression. Unfortunately, a patient cannot truly overcome depression until these impairments are addressed. A number of validated instruments are available to help clinicians assess functional impairment and monitor it throughout treatment. Clinicians must work with patients to develop personalized short-term and long-term functional goals and determine whether pharmacologic, nonpharmacologic, or rehabilitative treatment is needed.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Depressive Disorder, Major / drug therapy
  • Depressive Disorder, Major / rehabilitation*
  • Depressive Disorder, Major / therapy*
  • Disability Evaluation*
  • Humans
  • Remission Induction / methods*