BCR-ABL1-positive and JAK2 V617F-positive Clones in 23 Patients With Both Aberrations Reveal Biologic and Clinical Importance

Br J Haematol. 2017 Jan;176(1):135-139. doi: 10.1111/bjh.13932. Epub 2016 Feb 5.

Abstract

No abstract available

Keywords: BCR-ABL1; JAK2 V617F; chronic myeloid leukaemia; myeloproliferative neoplasm.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Clone Cells
  • Female
  • Fusion Proteins, bcr-abl / genetics*
  • Fusion Proteins, bcr-abl / metabolism
  • Humans
  • Janus Kinase 2 / genetics*
  • Janus Kinase 2 / metabolism
  • Male
  • Middle Aged
  • Mutation*
  • Myeloproliferative Disorders / enzymology*
  • Myeloproliferative Disorders / genetics*

Substances

  • BCR-ABL1 fusion protein, human
  • Fusion Proteins, bcr-abl
  • JAK2 protein, human
  • Janus Kinase 2