Management of chronic pruritus with a UV filtering topical cream

Dermatol Ther. Mar-Apr 2016;29(2):101-3. doi: 10.1111/dth.12309. Epub 2015 Nov 2.


Chronic pruritus is a common dermatological condition affecting 10-13% of the general population. UVB phototherapy has been demonstrated to be effective in relieving the symptoms of pruritus. However, phototherapy is rarely administered because the treatment is time-consuming and expensive, when compared to other topical drugs. In previous works, it has been reported that a topical cream, which selectively filters solar UVB can be used as a convenient alternative to traditional phototherapy. Here, we report the results of a pilot study aimed at assessing the effectiveness of the cream for treating pruritus. Seven patients with pruritus symptoms were included in the study. After 3 months of treatment (3 sessions per week), all patients noted improvement in pruritus symptoms. These preliminary results demonstrate that the novel topical cream could provide a convenient, low cost treatment for chronic pruritus patients.

Keywords: atopic dermatitis; eczema; phototherapy; pruritus.

MeSH terms

  • Administration, Cutaneous
  • Adult
  • Chronic Disease
  • Female
  • Follow-Up Studies
  • Humans
  • Pilot Projects
  • Pruritus / pathology
  • Pruritus / therapy*
  • Skin Cream
  • Treatment Outcome
  • Ultraviolet Therapy / methods*