Activated Muscle Satellite Cells Chase Ghosts

Cell Stem Cell. 2016 Feb 4;18(2):160-2. doi: 10.1016/j.stem.2016.01.008.

Abstract

The in vivo behaviors of skeletal muscle stem cells, i.e., satellite cells, during homeostasis and after injury are poorly understood. In this issue of Cell Stem Cell, Webster et al. (2016) now perform a tour de force intravital microscopic analysis of this population, showing that "ghost fiber" remnants act as scaffolds to guide satellite cell divisions after injury.

Publication types

  • Comment

MeSH terms

  • Cell Division
  • Muscle Fibers, Skeletal
  • Muscle, Skeletal*
  • Regeneration
  • Satellite Cells, Skeletal Muscle*
  • Stem Cells