[DOHaD: epidemiological researches]

Med Sci (Paris). 2016 Jan;32(1):21-6. doi: 10.1051/medsci/20163201005. Epub 2016 Feb 5.
[Article in French]


Epidemiological researches in the field of DOHaD are in favor of a role of early environment, including chemical (pesticides), physical (air pollution), nutritional or psychosocial environment, on child and adult health. Disentangling the different factors of environment that may affect health, especially over time, and identifying critical periods of exposure remains a major challenge. The biological mechanisms involved remain elusive in human beings. Nevertheless, it seems that whatever the nature of the exposure, epigenetic mechanisms are currently discussed to explain how the environment may alter biological systems over time.

Publication types

  • Review

MeSH terms

  • Adult
  • Diet
  • Disease / etiology*
  • Environment
  • Environmental Pollution / adverse effects
  • Environmental Pollution / statistics & numerical data
  • Epidemiologic Studies*
  • Epigenesis, Genetic / physiology
  • Female
  • Gene-Environment Interaction
  • Health*
  • Humans
  • Pregnancy
  • Prenatal Exposure Delayed Effects / epidemiology*
  • Prenatal Exposure Delayed Effects / etiology
  • Psychology