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. 2016 Jan;32(1):117-9.
doi: 10.1051/medsci/20163201019. Epub 2016 Feb 5.

[A Nobel Prize for DNA Repair]

[Article in French]
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Free article

[A Nobel Prize for DNA Repair]

[Article in French]
Bertrand Jordan. Med Sci (Paris). .
Free article

Abstract

This year's Nobel Prize for chemistry recognizes the seminal contributions of three researchers who discovered the existence and the basic mechanisms of DNA repair: base excision repair, mismatch repair, and nucleotide excision repair. They have since been joined by many scientists elucidating diverse aspects of these complex mechanisms that now constitute a thriving research field with many applications, notably for understanding oncogenesis and devising more effective therapies.

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