Malperfusion syndromes in aortic dissections

Vasc Med. 2016 Jun;21(3):264-73. doi: 10.1177/1358863X15625371. Epub 2016 Feb 8.


Aortic dissection remains a challenging clinical scenario, especially when complicated by peripheral malperfusion. Improvements in medical imaging have furthered understanding of the pathophysiology of malperfusion events in association with aortic dissection, including the elucidation of different mechanisms of branch vessel obstruction. Despite these advances, malperfusion syndrome remains a deadly entity with significant mortality. This review presents the latest knowledge regarding the pathogenesis of aortic dissection complicated by malperfusion syndrome, and discusses the diagnostic and therapeutic guidelines for management of this vicious entity.

Keywords: aortic diseases; minimally invasive; practice guidelines; stents; surgical procedures.

Publication types

  • Review

MeSH terms

  • Animals
  • Aortic Aneurysm / complications*
  • Aortic Aneurysm / diagnostic imaging
  • Aortic Aneurysm / physiopathology
  • Aortic Aneurysm / therapy
  • Aortic Dissection / complications*
  • Aortic Dissection / diagnostic imaging
  • Aortic Dissection / physiopathology
  • Aortic Dissection / therapy
  • Aortography
  • Blood Vessel Prosthesis
  • Blood Vessel Prosthesis Implantation / instrumentation
  • Endovascular Procedures / instrumentation
  • Hemodynamics*
  • Humans
  • Ischemia / diagnostic imaging
  • Ischemia / etiology*
  • Ischemia / physiopathology
  • Ischemia / therapy
  • Regional Blood Flow
  • Stents
  • Treatment Outcome
  • Ultrasonography, Doppler, Color
  • Vascular Patency